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I Byrjalsen Selected Research

salmon calcitonin (Calcimar)

4/2015Treatment of symptomatic knee osteoarthritis with oral salmon calcitonin: results from two phase 3 trials.
4/2015OA phenotypes, rather than disease stage, drive structural progression--identification of structural progressors from 2 phase III randomized clinical studies with symptomatic knee OA.
4/2011Oral salmon calcitonin reduces cartilage and bone pathology in an osteoarthritis rat model with increased subchondral bone turnover.
4/2011Lessons learned from the development of oral calcitonin: the first tablet formulation of a protein in phase III clinical trials.
6/2010Biochemical markers identify influences on bone and cartilage degradation in osteoarthritis--the effect of sex, Kellgren-Lawrence (KL) score, body mass index (BMI), oral salmon calcitonin (sCT) treatment and diurnal variation.
2/2010The effect of oral salmon calcitonin delivered with 5-CNAC on bone and cartilage degradation in osteoarthritic patients: a 14-day randomized study.

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I Byrjalsen Research Topics

Disease

10Bone Resorption
03/2013 - 09/2008
7Osteoarthritis
01/2021 - 02/2010
6Osteoporosis
03/2013 - 03/2008
3Knee Osteoarthritis
01/2021 - 04/2015
3Uterine Hemorrhage (Uterine Bleeding)
12/2007 - 03/2000
2Atherosclerosis
01/2001 - 02/2000
1Pain (Aches)
04/2015
1Fibrosis (Cirrhosis)
11/2013
1Portal Hypertension
11/2013
1End Stage Liver Disease
11/2013
1Osteoporotic Fractures
03/2013
1Neoplasm Metastasis (Metastasis)
01/2011
1Neoplasms (Cancer)
01/2011
1Prostatic Neoplasms (Prostate Cancer)
01/2011
1Liver Cirrhosis (Hepatic Cirrhosis)
10/2010
1Stress Fractures (Stress Fracture)
09/2009
1Hemorrhage
04/2007
1Rheumatoid Arthritis
03/2007
1Postmenopausal Osteoporosis
09/2000

Drug/Important Bio-Agent (IBA)

6salmon calcitonin (Calcimar)FDA LinkGeneric
04/2015 - 02/2010
5Biomarkers (Surrogate Marker)IBA
01/2021 - 06/2010
4CollagenIBA
01/2021 - 03/2008
4Collagen Type I (Type I Collagen)IBA
01/2011 - 12/2008
3Calcitonin (Calcitonin, Eel)FDA LinkGeneric
04/2011 - 09/2008
3Collagen Type II (Type II Collagen)IBA
06/2010 - 03/2007
2Proteins (Proteins, Gene)FDA Link
11/2013 - 03/2000
2TabletsIBA
03/2013 - 04/2011
2Pharmaceutical PreparationsIBA
04/2011 - 12/2008
2Hormones (Hormone)IBA
12/2007 - 04/2007
2Estrogens (Estrogen)FDA Link
12/2007 - 01/2001
2GestodeneIBA
04/2007 - 09/2000
2Raloxifene Hydrochloride (Evista)FDA Link
01/2001 - 02/2000
2CholesterolIBA
01/2001 - 02/2000
2Estradiol (Delestrogen)FDA LinkGeneric
01/2001 - 09/2000
1Extracellular Matrix ProteinsIBA
11/2013
1Matrix Metalloproteinases (MMPs)IBA
11/2013
1EpitopesIBA
11/2013
1Complement C3 (C3 Complement)IBA
11/2013
1Parathyroid Hormone (Parathormone)IBA
03/2013
1Teriparatide (Parathar)FDA Link
03/2013
1CreatinineIBA
04/2011
1Peptides (Polypeptides)IBA
04/2011
1Gonadal Steroid Hormones (Sex Hormones)IBA
04/2011
1strontium ranelate (protelos)IBA
04/2011
1Tartrate-Resistant Acid PhosphataseIBA
01/2011
1Ibandronic Acid (Boniva)FDA Link
10/2010
1OsteocalcinIBA
02/2010
1glutamyl- lysyl- alanyl- histidyl- aspartyl- glycyl- glycyl- arginineIBA
11/2008
1tiboloneIBA
11/2008
1Progestins (Progestagens)IBA
12/2007
1Levonorgestrel (Plan B)FDA LinkGeneric
04/2007
1Selective Estrogen Receptor Modulators (SERM)IBA
01/2001
1Progesterone Receptors (Progesterone Receptor)IBA
03/2000
1Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
03/2000
1LipidsIBA
02/2000

Therapy/Procedure

6Therapeutics
04/2011 - 09/2000
1Injections
03/2013
1Ligation
10/2010